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Updated: Jul 4, 2026
14:04
Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria
Published on: May 8, 2013
Unveiling the antibiotic resistance pattern in Staphylococcus aureus: A systematic review (2013-2024)
Snehal M Deshmukhe1, Chanda R Vyawahare2, Poonam V Suryawanshi3
1Department of Microbiology, Dr. D.Y. Patil Medical College, Hospital and Research Centre and Dr. D. Y. Patil Vidyapeeth, Pune 411018, Mahārāshtra, India.
World Journal of Experimental Medicine
|July 3, 2026
Summary
Antibiotic resistance in Staphylococcus aureus is a growing global concern. This study reveals significant regional variations in resistance patterns across India, highlighting high resistance to common antibiotics like methicillin.
Area of Science:
- Microbiology
- Infectious Diseases
- Public Health
Background:
- Staphylococcus aureus is a major nosocomial pathogen known for evolving antibiotic resistance mechanisms.
- Multidrug resistance in S. aureus is increasing globally, with notable regional variations in India.
Purpose of the Study:
- To identify and analyze the antibiotic resistance patterns of Staphylococcus aureus isolates across different geographical regions in India.
Main Methods:
- A systematic review of 26 research articles published between 2013 and 2024 was conducted.
- Data on study location, antibiotics used, and resistance percentages were extracted from Scopus, Google Scholar, and PubMed.
- Prospero registration number: CRD420251153034.
Main Results:
- Most studies originated from Northern (31%), Southern (27%), and Eastern (27%) India.
- Very high resistance rates were observed for beta-lactam antibiotics, including penicillin and methicillin, indicating a significant burden of methicillin-resistant S. aureus (MRSA).
- Fluoroquinolones and macrolides also showed high resistance, while linezolid, teicoplanin, chloramphenicol, and doxycycline demonstrated better activity.
Conclusions:
- This review highlights significant geographical trends in Staphylococcus aureus antibiotic resistance within India.
- Understanding these regional patterns is crucial for developing targeted strategies and future research on antibiotic resistance.
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