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Alcohol Consumption Is a Risk Factor of Surgical Site Infection After Minimally Invasive Surgery: A Secondary

Toshiya Akai1, Makoto Takeda1, Eisuke Booka1

  • 1Department of Surgery Hamamatsu University School of Medicine Hamamatsu Japan.

Annals of Gastroenterological Surgery
|July 3, 2026
PubMed
Abstract

Insights

Alcohol consumption is a significant risk factor for surgical site infections (SSI) in patients undergoing minimally invasive surgery (MIS) for gastrointestinal issues. Further research is needed to determine if alcohol abstinence pre-surgery can reduce SSI rates.

Area of Science:

  • Gastroenterological Surgery
  • Minimally Invasive Surgery (MIS)
  • Surgical Site Infections (SSI)

Background:

  • Surgical site infection (SSI) is a common postoperative complication, particularly in gastrointestinal surgery.
  • Minimally invasive surgery (MIS) is increasingly used, necessitating an understanding of its specific SSI risk factors.
  • Previous research suggests laparoscopic surgery has lower SSI rates than open surgery.

Purpose of the Study:

  • To identify risk factors for surgical site infections (SSI) in patients undergoing minimally invasive surgery (MIS).
  • To specifically examine SSI risk factors in the context of gastroenterological MIS.

Main Methods:

  • Secondary analysis of 529 patients from a clinical trial on gastroenterological surgery.
  • Patients undergoing elective MIS were divided into SSI and non-SSI groups.
  • Risk factors were analyzed using univariate and multivariate statistical methods.

Main Results:

  • Surgical site infection (SSI) occurred in 11.7% of patients within 30 days.
  • Univariate analysis identified male sex, alcohol consumption, bleeding, and operation time as associated with SSI.
  • Multivariate analysis revealed alcohol consumption as the only significant independent risk factor for SSI (OR: 2.818, p=0.001).

Conclusions:

  • Alcohol consumption is a significant risk factor for SSI in patients undergoing MIS for gastroenterological indications.
  • The study highlights the need for further investigation into the role of preoperative alcohol abstinence in preventing SSI.
Keywords:
alcohol consumptionminimally invasive surgerysurgical site infection

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