Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 4, 2026

Measuring Sub-23 Nanometer Real Driving Particle Number Emissions Using the Portable DownToTen Sampling System
08:59

Measuring Sub-23 Nanometer Real Driving Particle Number Emissions Using the Portable DownToTen Sampling System

Published on: May 22, 2020

TREADS: tyre nanoparticles produced using a bench-top tyre wear simulator.

David P O'Loughlin1,2, Charlotte Gisbourne3, Coco Day3

  • 1MRC Toxicology Unit Gleeson Building, Tennis Court Road Cambridge CB2 1QR UK mm2312@cam.ac.uk.

Environmental Science. Nano
|July 3, 2026
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of livestock-related air pollution on public health: A nationwide population-based study on COVID-19 in the Netherlands.

Environment international·2026
Same author

Functional characterisation of tumour suppressor PDCD4 reveals previously undisclosed role in the control of cell adhesion.

Nucleic acids research·2026
Same author

Inhibiting translation elongation by reducing eIF5A activity induces feedback inhibition of initiation, limiting tumour cell proliferation.

Nature communications·2025
Same author

Near-cognate tRNAs dominate codon decoding times in simulated ribosomes.

Nucleic acids research·2025
Same author

Fabrication of microplastic and nanoplastic particles and fibres for use in pulmonary toxicity studies.

Particle and fibre toxicology·2025
Same author

Human gut bacteria bioaccumulate per- and polyfluoroalkyl substances.

Nature microbiology·2025

The Tyre Rubber Emission And Debris System (TREADS) generates high concentrations of nano-tyre particles for toxicological studies. This portable, low-cost instrument offers reproducible, user-friendly nano-tyre particle generation for research.

Area of Science:

  • Environmental Science
  • Toxicology
  • Materials Science

Background:

  • Tyre wear particles (TPs) are a significant source of microplastic pollution.
  • Understanding the toxicology of nano-TPs requires standardized generation methods.
  • Existing methods for TPs lack portability and reproducibility.

Purpose of the Study:

  • To introduce the Tyre Rubber Emission And Debris System (TREADS) for generating nano-TPs.
  • To assess the characteristics and concentration of TPs produced by TREADS.
  • To evaluate TREADS' suitability for toxicological assessments.

Main Methods:

  • TREADS was used to generate sub-micron tyre wear particles.
  • Particle size distribution was analyzed and compared to literature.

More Related Videos

Testing of Nanoparticle Release from a Composite Containing Nanomaterial Using a Chamber System
04:55

Testing of Nanoparticle Release from a Composite Containing Nanomaterial Using a Chamber System

Published on: November 22, 2016

Related Experiment Videos

Last Updated: Jul 4, 2026

Measuring Sub-23 Nanometer Real Driving Particle Number Emissions Using the Portable DownToTen Sampling System
08:59

Measuring Sub-23 Nanometer Real Driving Particle Number Emissions Using the Portable DownToTen Sampling System

Published on: May 22, 2020

Testing of Nanoparticle Release from a Composite Containing Nanomaterial Using a Chamber System
04:55

Testing of Nanoparticle Release from a Composite Containing Nanomaterial Using a Chamber System

Published on: November 22, 2016

  • Particle concentration was measured during one-hour test cycles.
  • TP characteristics (shape, temperature) were observed.
  • Main Results:

    • TREADS produced high concentrations of sub-micron TPs (2-6 × 10^6 cm^-3).
    • Particle size distribution matched established nano-TP literature.
    • Particles were round, indicative of gas-to-particle conversion at 37-44 °C.
    • Consistent particle generation was observed across different tyres.

    Conclusions:

    • TREADS is a novel, portable, and low-cost system for generating nano-TPs.
    • The system provides reproducible and user-friendly nano-TP generation.
    • TREADS is suitable for toxicological assessments of nano-TPs without environmental contamination.