Related Experiment Video
Updated: Jul 4, 2026
09:55
Troubleshooting and Quality Assurance in Hyperpolarized Xenon Magnetic Resonance Imaging: Tools for High-Quality Image Acquisition
Published on: January 5, 2024
Suppression of Oscillation and Ghosting in RF-Spoiled Gradient-Echo-Based Dynamic Imaging.
Jae-Youn Keum1, Jang-Yeon Park1,2
1Department of Intelligent Precision Healthcare Convergence, Sungkyunkwan University, Suwon, Republic of Korea.
Magnetic Resonance in Medicine
|July 3, 2026
Summary
This study introduces a new method to eliminate ghosting and oscillation artifacts in dynamic MRI scans caused by magnetization. The technique improves image quality for high-temporal-resolution applications like fMRI.
Area of Science:
- Magnetic Resonance Imaging (MRI)
- Biophysics
- Medical Imaging Technology
Background:
- Radiofrequency (RF)-spoiled gradient-echo imaging is prone to oscillation and ghosting artifacts.
- These artifacts stem from the pseudo-steady state (PSS) of magnetization.
- Dynamic imaging applications require artifact suppression for accurate results.
Purpose of the Study:
- To suppress oscillation and ghosting artifacts in RF-spoiled gradient-echo-based cine imaging.
- To address limitations caused by the pseudo-steady state (PSS) of magnetization.
- To enhance image quality for ultrahigh temporal resolution MRI.
Main Methods:
- Extended RF phase-cycle-adapted averaging to cine imaging with intertrial RF phase-cycle shifts.
- Validated the method via theoretical analysis, 2D Bloch simulations, and phantom/human brain imaging at 3T.
- Evaluated performance using spectral analysis and temporal signal-to-noise ratio (tSNR) maps.
Main Results:
- Successfully suppressed ghosting artifacts and oscillatory components in phantom and human brain images.
- Averaging over specific trials, determined by PSS magnetization phase, fully eliminated artifacts.
- Reduced trial averaging significantly mitigated artifacts, demonstrating robust performance and improved tSNR.
Conclusions:
- Theoretically investigated PSS magnetization behavior in RF-spoiled gradient-echo cine imaging.
- Demonstrated an effective method for suppressing oscillation and ghosting artifacts.
- The method offers a valuable tool for ultrahigh temporal resolution MRI applications, including fMRI.
Related Concept Videos
01:12Double Resonance Techniques: Overview
Double resonance techniques in Nuclear Magnetic Resonance (NMR) spectroscopy involve the simultaneous application of two different frequencies or radiofrequency pulses to manipulate and observe two distinct nuclear spins. One important application of double resonance is spin decoupling, which selectively suppresses coupling with one type of nucleus while observing the NMR signal from another nucleus, simplifying the spectrum and enhancing resolution.
Spin decoupling is usually achieved by...
Spin decoupling is usually achieved by...
01:04¹³C NMR: ¹H–¹³C Decoupling
The probability of having two carbon-13 atoms next to each other is negligible because of the low natural abundance of carbon-13. Consequently, peak splitting due to carbon-carbon spin-spin coupling is not observed in spectra. However, protons up to three sigma bonds away split the carbon signal according to the n+1 rule, resulting in complicated spectra.
A broadband decoupling technique is used to simplify these complex, sometimes overlapping, signals. Broadband decoupling relies on a...
A broadband decoupling technique is used to simplify these complex, sometimes overlapping, signals. Broadband decoupling relies on a...
01:14NMR Spectrometers: Resolution and Error Correction
When magnetic nuclei in a sample achieve resonance and undergo relaxation, the signal detected in NMR is an approximately exponential free induction decay. Fourier transform of an exponential decay yields a Lorentzian peak in the frequency domain. Lorentzian peaks in an NMR spectrum are defined by their amplitude, full width at half maximum, and position, where the peak width is governed by the spin-spin relaxation time alone. In real experiments, however, the applied magnetic field is rendered...
01:17NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences
A pulse is a short burst of radio waves distributed over a range of frequencies that simultaneously excites all the nuclei in the sample. Upon passing a radio frequency pulse along the x-axis, the nuclei absorb energy corresponding to their Larmor frequencies and achieve resonance. This shifts the net magnetization vector from the z-axis toward the transverse plane. This angle of rotation of the magnetization vector, or the flip angle, is proportional to the duration and intensity of the pulse.
01:20¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)
When proton-coupled carbon-13 spectra are simplified by a broadband proton decoupling technique, structural information about the coupled protons is lost. Distortionless enhancement by polarization transfer (DEPT) is a technique that provides information on the number of hydrogens attached to each carbon in a molecule. While the DEPT experiment utilizes complex pulse sequences, the pulse delay and flip angle are specifically manipulated. The resulting signals have different phases depending on...