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Processes in psychotherapy: A scoping review with LLM-assisted clustering
Stefan G Hofmann1, Lucie Pahlen2, Marlon Westhoff1
1Philipps-Universität Marburg, Department of Psychology, Schulstraße 12, D-35032 Marburg, Germany.
Clinical Psychology Review
|July 3, 2026
Summary
Research on therapeutic change processes remains stagnant, with common factors like therapeutic alliance dominating studies. Despite calls for advancement, the focus has not shifted, limiting progress in clinical psychology.
Area of Science:
- Clinical Psychology
- Psychotherapy Research
- Treatment Efficacy
Background:
- Clinical psychology shows limited progress in treatment efficacy and intervention refinement.
- Traditionally, common factors like therapeutic alliance and empathy are key to change.
- Understanding processes of change is crucial for advancing psychological science.
Purpose of the Study:
- To systematically survey and analyze research trends on processes of change in psychological interventions.
- To identify and categorize the various processes of therapeutic change investigated in recent literature.
- To assess shifts in research focus and volume concerning therapeutic processes over time.
Main Methods:
- Systematic literature review of 778 studies reporting on 684 processes of therapeutic change since 2007.
- AI-assisted human-in-the-loop clustering procedure for organizing processes.
- Utilized OpenAI's GPT-5 nano model to define 32 distinct process clusters.
Main Results:
- Common factors (therapeutic alliance, collaborative processes, interpersonal functioning) formed the largest cluster (20.6%).
- Specific factors, particularly from cognitive behavioral therapy (cognitive appraisal, belief change), constituted the remaining processes.
- Research focus and study volume on therapeutic processes have remained largely unchanged.
Conclusions:
- Despite recognized needs, research on therapeutic processes has not substantially evolved.
- The predominant focus remains on common factor processes, potentially hindering innovation.
- Further investigation into diverse therapeutic processes is needed to improve treatment efficacy.
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