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Updated: Jul 5, 2026
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Motor Dual-Tasks for Gait Analysis and Evaluation in Post-Stroke Patients
Published on: March 11, 2021
Admission cognitive function independently predicts discharge walking function and functional independence after
Jeong-Soo Kim1, Eu Jeong Ko2, In-Geon Hwang3
1Department of Physical Therapy, College of Health Science, Yonsei University, Wonju, Republic of Korea; Department of Mirae Rehabilitation Research, Seoul Rehabilitation Hospital, Seoul, Republic of Korea.
Summary
Cognitive impairment after stroke significantly impacts rehabilitation outcomes. Early assessment using the Mini-Mental State Examination (MMSE) predicts walking ability and independence at discharge.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Cognitive Science
Background:
- Post-stroke cognitive impairment is common and affects recovery.
- Its independent impact on functional outcomes in large cohorts remains unclear.
Purpose of the Study:
- To evaluate if admission cognitive function, assessed by the Mini-Mental State Examination (MMSE), independently predicts functional recovery.
- Specifically, to assess prediction of walking function and independence at discharge from inpatient stroke rehabilitation.
Main Methods:
- A multicenter retrospective cohort study of 577 stroke patients.
- Patients categorized by admission MMSE scores: normal (≥24), mild (18-23), and moderate-to-severe (<18).
- Multivariable regression analyzed predictors of discharge Functional Ambulation Category (FAC) and Modified Barthel Index (MBI), adjusting for covariates.
Main Results:
- Admission MMSE scores independently predicted discharge FAC and MBI.
- Patients with moderate-to-severe impairment had significantly lower discharge FAC and MBI.
- An MMSE cut-off of 20 demonstrated good predictive ability for functional independence (AUC=0.771).
Conclusions:
- Early cognitive assessment via MMSE is crucial for predicting stroke rehabilitation outcomes.
- An MMSE score of 20 can identify patients at risk for poorer functional recovery.
- Routine cognitive screening upon admission is recommended for optimizing patient care.
