Related Experiment Video
Updated: Jul 5, 2026

Extraction of Extracellular Vesicles from Whole Tissue
Published on: February 7, 2019
Tissue derived extracellular vesicles advance from disease mechanisms to clinical application
Rui Dai1,2, Jiayan Gao3, Shenyuan Chen1,2
1Center of Laboratory Medicine, Aoyang Institute of Cancer, Affiliated Aoyang Hospital of Jiangsu University, 279 Jingang Road, Suzhou, 215600, Jiangsu, China.
None:
Extracellular vesicles (EVs), nanoscale membranous structures secreted by cells, have gradually evolved from being passive communication vehicles and could now contribute to the development of engineerable theranostic nanoplatforms. Among these, tissue-derived extracellular vesicles (Ti-EVs) have demonstrated the potential for higher yields and may better reflect the physiological or pathological state of the tissue microenvironment compared to cell-culture counterparts. These advantages may make Ti-EVs potentially valuable tools for studying disease mechanisms and developing targeted therapies. This review provides a comprehensive overview of Ti-EVs, including their isolation, characterization, and biological functions in various diseases. By summarizing the latest research and technological advances, we evaluate the potential of Ti-EVs to serve as modulators of disease progression, and discuss the challenges in their clinical applications.
More Related Videos
07:03Isolation, Characterization, and Therapeutic Application of Extracellular Vesicles from Cultured Human Mesenchymal Stem Cells
Published on: September 23, 2022
09:57Isolation and Analysis of Traceable and Functionalized Extracellular Vesicles from the Plasma and Solid Tissues
Published on: October 17, 2022
Related Concept Videos
Overview of Exosomes
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...
Clinical Applications of Epidermal Stem Cells