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Body Weight and Insulin Resistance Indicators Among Children

Monika Gesek1, Danuta Zarzycka1, Arkadiusz Jędrzejewski1

  • 1Department of Pediatrics and Pediatric Nursing, Department of Integrated Nursing Care, Faculty of Health Sciences, Medical University of Lublin, Lublin, Poland.

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
|July 4, 2026
PubMed

Insights

Childhood body weight is linked to insulin resistance. Overweight children show higher insulin resistance, increasing risks for metabolic disorders and long-term health issues.

Area of Science:

  • Pediatrics
  • Metabolic Health
  • Endocrinology

Background:

  • Childhood body weight is a significant factor in developing insulin resistance.
  • Insulin resistance in children poses risks for future metabolic disorders.

Purpose of the Study:

  • To investigate the relationship between body weight and insulin resistance indicators in children.
  • To analyze how body weight influences biochemical markers of insulin resistance.

Main Methods:

  • Cross-sectional study of 99 children (aged 8-14) at University Children's Hospital, Lublin (2023-2024).
  • Collected anthropometric data (weight, height, BMI), clinical data (sex, age, obesity classification), and biochemical data (glucose, insulin).
  • Assessed insulin resistance using Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) and Quantitative Insulin Sensitivity Check Index (QUICKI).

Main Results:

  • Insulin resistance was diagnosed in 43.43% of the studied children.
  • Children with insulin resistance exhibited a significantly higher Body Mass Index (BMI) (P=0.001).
  • Insulin resistance was more prevalent in overweight children compared to normal or underweight children.

Conclusions:

  • Overweight and obesity in children are strongly associated with insulin resistance.
  • Early diagnosis of insulin resistance is crucial for implementing preventive strategies, like lifestyle modifications.
  • Addressing childhood insulin resistance can mitigate the risk of metabolic disorders and long-term health complications.

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