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Updated: Jul 6, 2026
A Method for Quantifying Upper Limb Performance in Daily Life Using Accelerometers
Published on: April 21, 2017
A methodological overview of new measure development for the Limb Injury Measurement Battery for Quality of Life
Aaron J Boulton1, Seung W Choi2, Callie E Tyner1
1Center for Health Assessment Research and Translation, University of Delaware, 100 Discovery Blvd, Newark, DE, 19713, USA.
Purpose:
To describe the data analytic strategy used to develop new quality-of-life measures for the Limb Injury Measurement Battery for Quality of Life (LIMB-QOL).
Methods:
Several item pools were created and administered to a large sample of individuals with a history of major extremity injury or limb loss (n = 603). Item analyses adhered to modern psychometric standards (e.g., PROMIS®, COSMIN) and aimed to create several item response theory-based (IRT) item banks based on the graded response model. Items were removed iteratively based on pre-defined criteria and IRT model assumptions were met for the final item pools (monotonicity, unidimensionality, local item independence); differential item functioning, test-retest reliability, and convergent validity were then evaluated. Computer adaptive test and short-form versions of final item banks were created and examined using data simulation.
Results:
Item analyses led to the development of 8 new item banks and two fixed-length scales. These 10 new LIMB-QOL measures demonstrated initial evidence of reliability (α range = 0.94-0.98, test-retest ICC range: 0.68-0.91) and convergent validity for use in individuals with a history of major extremity injury or limb loss, and abbreviated formats of the full item banks exhibited comparable performance.
Conclusion:
The new LIMB-QOL measures demonstrated strong psychometric properties and can be used to collect patient-reported assessments of quality of life following major extremity injury and limb loss. The analytic strategy described herein exemplifies how the PROMIS methodology can be utilized to design IRT-based patient-reported outcome measures to fill measurement gaps for specific clinical populations.
