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Updated: Jul 6, 2026
08:09
Annotation of Plant Gene Function via Combined Genomics, Metabolomics and Informatics
Published on: June 17, 2012
AtFusionDB: A Comprehensive Database of Fusion Transcripts in Model Plant Arabidopsis thaliana.
1Department of Chemistry, Gargi College, University of Delhi, Siri Fort Road, New Delhi, India.
Methods in Molecular Biology (Clifton, N.J.)
|July 4, 2026
Summary
This study introduces AtFusionDB, the first database for plant-specific fusion transcripts. It provides valuable information on gene and transcript fusions in Arabidopsis thaliana, aiding plant research.
Area of Science:
- Molecular Biology
- Bioinformatics
- Plant Science
Background:
- Fusion transcripts, chimeric RNAs from RNA or DNA level fusions, are increasingly identified with high-throughput sequencing.
- While known as cancer biomarkers, they also occur in normal human physiology and have been reported in plants.
- No dedicated web resource currently exists for plant-specific fusion transcripts.
Purpose of the Study:
- To describe the first plant-specific database of fusion transcripts, AtFusionDB.
- To provide a centralized resource for fusion transcript information in plants.
- To facilitate research on gene/transcript fusion in the model plant Arabidopsis thaliana.
Main Methods:
- Development of a dedicated web resource (AtFusionDB).
- Data compilation of fusion transcripts identified in Arabidopsis thaliana.
- Database curation and accessibility via a web interface (http://www.nipgr.res.in/AtFusionDB).
Main Results:
- Establishment of AtFusionDB, the first database for plant fusion transcripts.
- The database contains information on fusion transcripts identified in Arabidopsis thaliana.
- Provides a valuable resource for exploring gene/transcript fusion events in plants.
Conclusions:
- AtFusionDB is a significant resource for plant molecular biology research.
- The database aids in understanding the role and prevalence of fusion transcripts in plants.
- Facilitates further investigation into plant gene and transcript fusion mechanisms.
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