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Addressing Obstetric and Gynecologic Needs in Thalassemia
Evangelia Vlachodimitropoulou1, Marina Baldini1, Hanny Al-Samkari1
1Department of Obstetrics and Gynaecology, King's College Hospital, London, UK; Unit of Medicine and Metabolic Disease, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Division of Hematology and Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Hematology Section, Cancer and Blood Disease Institute, Children's Hospital Los Angeles, University of Southern California, Los Angeles, California; Division of Hematology, University of Toronto, Toronto, Ontario, Canada; Scarborough Health Network, Scarborough, Ontario, Canada; Department of Pediatrics, Division of Hematology/Oncology, Weill Cornell Medicine, New York, New York; Division of Hematology and Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon; Department of Pediatrics & Thalassemia Center, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand; Center for Research on Rare Blood Disorders (CR-RBD) and Thalassemia & Sickle Cell Center, Burjeel Cancer Institute, Burjeel Medical City, Abu Dhabi, United Arab Emirates; and Department of Public Health & Epidemiology, Khalifa University, Abu Dhabi, United Arab Emirates.
Abstract:
Thalassemia represents a spectrum of rare, inherited blood disorders associated with a range of disease- and treatment-related complications. Thalassemia can have a significant effect on the female reproductive system, and obstetrics and gynecology specialists have a key role to play in managing the disease as part of a multidisciplinary team. Here, we review the role of obstetrics and gynecology specialists in thalassemia from puberty to pregnancy and postnatal support, including diagnosis and management of complications, supporting patients through pubertal and fertility issues and the risks associated with pregnancy.
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