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Addressing Obstetric and Gynecologic Needs in Thalassemia.
Evangelia Vlachodimitropoulou1, Marina Baldini1, Hanny Al-Samkari1
1Department of Obstetrics and Gynaecology, King's College Hospital, London, UK; Unit of Medicine and Metabolic Disease, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Division of Hematology and Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Hematology Section, Cancer and Blood Disease Institute, Children's Hospital Los Angeles, University of Southern California, Los Angeles, California; Division of Hematology, University of Toronto, Toronto, Ontario, Canada; Scarborough Health Network, Scarborough, Ontario, Canada; Department of Pediatrics, Division of Hematology/Oncology, Weill Cornell Medicine, New York, New York; Division of Hematology and Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon; Department of Pediatrics & Thalassemia Center, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand; Center for Research on Rare Blood Disorders (CR-RBD) and Thalassemia & Sickle Cell Center, Burjeel Cancer Institute, Burjeel Medical City, Abu Dhabi, United Arab Emirates; and Department of Public Health & Epidemiology, Khalifa University, Abu Dhabi, United Arab Emirates.
Thalassemia, a rare inherited blood disorder, significantly impacts female reproduction. Obstetrics and gynecology specialists are crucial for managing complications from puberty through pregnancy and postpartum care.
Area of Science:
- Hematology
- Reproductive Medicine
- Genetics
Background:
- Thalassemia encompasses rare inherited blood disorders with diverse complications.
- These disorders significantly affect the female reproductive system.
- Multidisciplinary care is essential for managing thalassemia patients.
Purpose of the Study:
- To review the critical role of obstetrics and gynecology specialists in thalassemia management.
- To outline the care pathway for female thalassemia patients from puberty to postpartum.
- To highlight the diagnosis and management of reproductive complications.
Main Methods:
- Literature review focusing on obstetrics and gynecology in thalassemia.
- Analysis of disease progression and treatment effects on female reproductive health.
- Synthesis of current guidelines and clinical practices.
Main Results:
- Obstetrics and gynecology specialists manage pubertal, fertility, and pregnancy-related issues.
- Early diagnosis and management of complications are vital.
- Specialists provide essential support throughout the reproductive lifespan.
Conclusions:
- Integrated care by obstetrics and gynecology specialists improves outcomes for women with thalassemia.
- Addressing reproductive health is integral to comprehensive thalassemia management.
- Continued research and collaboration are needed to optimize care.
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