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POEMS syndrome: A case report
Maryam Masjedi Esfahani1, Shamim Shafieioun1, Hajar Zahedimehr1
1Radiology Department, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Radiology Case Reports
|July 6, 2026
Summary
POEMS syndrome, a rare plasma cell disorder, presents with polyneuropathy and organomegaly. Characteristic imaging findings, including nerve root enhancement and mixed bone lesions, aid early diagnosis and differentiate it from other neuropathies.
Area of Science:
- Neurology
- Oncology
- Radiology
Background:
- POEMS syndrome is a rare multisystem disorder linked to monoclonal plasma cell neoplasms.
- Diagnosis is often delayed due to overlapping symptoms with other neuropathies, impacting patient prognosis.
- Key features include polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes.
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