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From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding
Published on: March 24, 2018
Crystal structure of the meso compound (2R,6S)-4-(5-bromo-pyrimidin-2-yl)-2,6-di-methyl-morpholine
Paul R Palme1, Richard Goddard2, Markus Leutzsch2
1Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Wolfgang-Langenbeck-Str. 4, 06120 Halle (Saale), Germany.
None:
The title compound, C10H14N3OBr, was prepared by a nucleophilic aromatic substitution reaction between 2,6-di-methyl-morpholine and 2-chloro-pyrimidine, followed by bromination of the pyrimidine ring. The compound crystallizes in the monoclinic system (space group P21/c) with four mol-ecules in the unit cell (Z = 4). The mol-ecule exhibits approximate C S point-group symmetry (r.m.s. deviation: 0.1072 Å). The arrangement of the mol-ecules in the solid state is dominated by close packing. C-H⋯N contacts between pyrimidinyl rings in adjacent mol-ecules with an R 2 2(6) motif are encountered, whereas the bromine atom does not exhibit any short contacts that could be regarded as halogen bonds.
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