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Microbes and Climate Change01:27

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Microorganisms are pivotal agents in Earth's biogeochemical cycles, significantly influencing climate dynamics through their metabolic activities. These microbes modulate the levels of key greenhouse gases by both contributing to and helping mitigate climate change.Microbial Contributions to Greenhouse Gas EmissionsRising global temperatures accelerate microbial metabolism, which, in turn, speeds up the decomposition of organic matter. This process releases carbon dioxide (CO₂) through...
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Microorganisms play a pivotal role in maintaining ecosystem balance by recycling essential elements such as carbon, nitrogen, and phosphorus, as well as supporting processes like bioremediation, wastewater treatment, and biofuel production.Microbes in Elemental CyclesIn the carbon cycle, microorganisms decompose organic matter, releasing carbon dioxide via aerobic respiration. This carbon dioxide is subsequently used by photosynthetic organisms to synthesize organic compounds, closing the...
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Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
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Updated: Jul 7, 2026

BioMEMS: Forging New Collaborations Between Biologists and Engineers
07:26

BioMEMS: Forging New Collaborations Between Biologists and Engineers

Published on: November 1, 2007

Engineering Biology's Vital Role for Climate Mitigation.

Lionel John Clarke1

  • 1Department of BioEngineering Imperial College London UK.

Engineering Biology
|July 6, 2026
PubMed
Summary

Engineering biology offers transformative solutions for climate mitigation by replacing fossil fuels, chemicals, and materials with renewable alternatives. Successful de-fossilisation requires integrating these technologies into viable supply chains and stable policy frameworks.

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Area of Science:

  • Environmental Science
  • Biotechnology
  • Chemical Engineering

Background:

  • Significant progress in de-fossilising energy via renewable electricity generation.
  • Carbon-centric sectors like transport, chemicals, and agriculture remain predominantly fossil-based.
  • Current bio-based alternatives (biofuels, bio-plastics) supply a small fraction of global demand, facing commercialization challenges.

Purpose of the Study:

  • To examine the potential of engineering biology in climate change mitigation.
  • To identify how engineering biology can facilitate the de-fossilisation of fuels, chemicals, materials, and food systems.
  • To explore technological options and commercial opportunities offered by engineering biology.

Main Methods:

  • Review of current limitations in replacing fossil carbon with renewable carbon.
  • Discussion of engineering biology advancements, including synthetic biology, bioprocess engineering, and electro-biological systems.
  • Analysis of constraints such as feedstock availability, sustainability, capital intensity, certification, and policy.

Main Results:

  • Engineering biology presents potentially transformative technological options for de-fossilisation.
  • Innovative commercial opportunities exist within sectors currently reliant on fossil carbon.
  • Technical developments and investment alone are insufficient for impact.

Conclusions:

  • The contribution of engineering biology to climate mitigation hinges on integration into economically viable supply chains.
  • Stable, long-term policy frameworks are crucial for supporting investment and large-scale deployment.
  • Successful de-fossilisation requires a holistic approach combining technological advancement, economic viability, and supportive policies.