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Updated: Jul 7, 2026

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Published on: September 12, 2019
Primary Hepatic Histiocytic Sarcoma Mimicking Hepatocellular Carcinoma
Evgenia Tziava1, Aikaterini Leventi1, Maria Arnaouti2
1Department of Surgical Oncology, Agios Savvas Anticancer Hospital, Athens, Greece.
Primary hepatic histiocytic sarcoma (HS) is a rare liver cancer. This case report details a challenging diagnosis and reviews key features of this aggressive malignancy.
Area of Science:
- Oncology
- Pathology
- Gastroenterology
Background:
- Primary hepatic histiocytic sarcoma (HS) is an exceptionally rare liver malignancy.
- It presents with nonspecific clinical and morphological features, mimicking other high-grade liver tumors.
- Diagnosis is often challenging due to its rarity and overlapping features.
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