Related Experiment Video
Updated: Jul 7, 2026
03:47
Workflow and Framework for Collecting and Implementing Point-of-Care Ultrasound Data in the Management of Heart Failure Patients
Published on: July 12, 2024
Comprehensive Framework of Heart Failure with Preserved Ejection Fraction Management for Hospitalists: A Scoping
Jeffery Northway1, John Park1, Keith Mankowitz2
1Saint Louis University School of Medicine.
Journal of Brown Hospital Medicine
|July 6, 2026
Summary
Heart failure with preserved ejection fraction (HFpEF) management is complex due to comorbidities. Sodium-glucose cotransporter-2 (SGLT2) inhibitors show promise in reducing hospitalizations and cardiovascular death.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Heart failure with preserved ejection fraction (HFpEF) affects nearly half of heart failure patients, especially older adults with comorbidities.
- HFpEF is characterized by diastolic dysfunction, ventricular stiffness, and impaired filling, influenced by inflammation, endothelial dysfunction, and fibrosis.
- Management is challenging due to common comorbidities like hypertension, diabetes, atrial fibrillation, CKD, obesity, and CAD.
Purpose of the Study:
- To review current guideline-directed medical therapy (GDMT) for HFpEF.
- To provide a practical framework for hospital-based management of HFpEF.
Main Methods:
- Review of current literature and clinical guidelines on HFpEF management.
- Focus on evidence-based therapies and comprehensive comorbidity management.
Main Results:
- Sodium-glucose cotransporter-2 (SGLT2) inhibitors demonstrate strong evidence for reducing HF hospitalizations and cardiovascular death.
- Other therapies like ARNIs, finerenone, and GLP-1 receptor agonists show promise in specific populations.
- Hospitalists are crucial for early HFpEF recognition and GDMT initiation.
Conclusions:
- SGLT2 inhibitors are a key therapy for HFpEF.
- Comprehensive management of comorbidities is essential for optimal HFpEF care.
- Hospitalists play a vital role in improving HFpEF outcomes through timely intervention and management.
Related Concept Videos
01:30Heart Failure V: Medical Management
Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
01:30Heart Failure IV: Classification and Diagnostic Evaluation
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
01:17Pathophysiology of Heart Failure
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
01:30Heart Failure VII: Nursing Interventions
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
01:22Heart Failure VI: Adjunct Therapies
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
01:21Rheumatic Heart Disease III: Medical Management
Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...