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Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
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Friend or foe? IFNλ drives fibrosis

Ivan Zanoni1

  • 1Harvard Medical School, Boston Children's Hospital , Boston, MA, USA.

The Journal of Experimental Medicine
|July 6, 2026
PubMed
Summary

Type III interferons (IFNλ) are immune mediators primarily acting at mucosal surfaces. New research shows IFNλ also signals in kidney fibroblasts, contributing to renal fibrosis.

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