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Updated: Jul 7, 2026

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Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate (HoLEP).
Published on: March 6, 2018
Hospital-based direct cost comparison between open simple prostatectomy and HoLEP
Mariela Montanile1, Wilmer Soliz2, Horacio Sanguinetti3,2
1Centro Argentino de Urologia, Buenos Aires, Argentina. marielamontanile@gmail.com.
World Journal of Urology
|July 6, 2026
Summary
Holmium laser enucleation of the prostate (HoLEP) is more cost-effective than open simple prostatectomy (OSP) for benign prostatic hyperplasia, despite higher initial procedure costs. HoLEP leads to lower overall hospital expenses due to reduced resource use.
Area of Science:
- Urology
- Health Economics
- Surgical Outcomes
Background:
- Benign prostatic hyperplasia (BPH) is a common condition requiring surgical intervention.
- Open simple prostatectomy (OSP) and holmium laser enucleation of the prostate (HoLEP) are established surgical treatments for BPH.
- Understanding the economic impact of different surgical approaches is crucial for healthcare management.
Purpose of the Study:
- To compare the hospital-based direct costs of care for BPH patients undergoing OSP versus HoLEP.
- To identify the primary drivers of cost differences between these two surgical procedures.
Main Methods:
- Retrospective analysis of hospital billing data and medical records.
- Inclusion of direct costs: personnel, facilities, equipment, consumables, and medications.
- Cost data converted to USD using official exchange rates.
Main Results:
- Fifty patients were analyzed (25 OSP, 25 HoLEP) with comparable demographics and prostate volumes.
- OSP patients experienced longer hospital stays and higher ICU admission rates, leading to significantly higher total direct costs (USD 4,676 vs. USD 3,360; p < 0.001).
- HoLEP had higher initial procedural costs but resulted in lower overall hospital costs.
Conclusions:
- HoLEP is associated with lower short-term hospital-based direct costs compared to OSP.
- Reduced postoperative resource utilization is the main factor contributing to HoLEP's cost-effectiveness.
- These findings offer valuable economic data for healthcare institutions when selecting BPH surgical treatments.
