Decoding Sensitive Skin Syndrome: International Expert Advisory Insights on Management From India and the United...

Sensitive skin syndrome (SSS) is a common self-reported condition, more prevalent in women, characterized by redness, irritation, and discomfort in response to various triggers. SSS remains a multifactorial condition with overlapping symptoms and no clear correlation between sensory complaints and observable signs, complicating both diagnosis and management. This study aimed to establish expert-driven recommendations for the diagnosis, treatment, and holistic care of SSS.

In May 2024, a panel of 11 international dermatologists reviewed literature, answered questionnaires, and convened to integrate clinical experience and emerging evidence into expert recommendations on SSS diagnosis, treatment, and holistic care.

Experts determined that SSS is a distinct medical condition requiring systematic evaluation. Recommended diagnostic approaches included patient history, physical examination, validated self-assessment tools such as Sensitive Scale-10, dermoscopy, and sensory reactivity testing to exclude other conditions. Key findings included overlap between SSS and hyperhidrosis, supporting cross-screening, and management strategies recommending low- to medium-potency topical corticosteroids for flares and pimecrolimus as a steroid-free long-term option. Dermocosmetics with panthenol, glycerin, ceramides, hyaluronic acid, and niacinamide were recommended for barrier repair, and the Cleanse, Treat, Moisturize, Protect (CTMP®) regimen was emphasized as a cornerstone of holistic skincare.

The advisory board highlighted that underdiagnosis and low awareness hinder effective management. Combining pharmacological and dermocosmetic strategies improves outcomes, but education of both clinicians and patients remains a challenge.

SSS is a clinically relevant condition requiring structured diagnostics, recognition of comorbidities, and integrated treatment. Greater awareness and education are essential to improve care.  .