Standardizing Normal Pressure Hydrocephalus Diagnosis: The Interdisciplinary Lausanne's Protocol

Area of Science:

• Neurology
• Neurosurgery
• Geriatrics

Background:

• Idiopathic normal pressure hydrocephalus (iNPH) presents diagnostic challenges.
• It is a reversible condition affecting gait, cognition, and urinary function.
• A structured multidisciplinary protocol was developed to enhance iNPH diagnosis.

Purpose of the Study:

• To evaluate the effectiveness of a novel, structured multidisciplinary protocol for diagnosing iNPH.
• To streamline the diagnostic pathway for patients with suspected iNPH.
• To assess the protocol's impact on patient management and outcomes.

Main Methods:

• Implemented a protocol involving neurological, neuropsychological, and physical therapy assessments.
• Included a CSF tap test with pre- and post-test evaluations.
• Utilized interdisciplinary consultations and an expert board for treatment recommendations.

Main Results:

• Analyzed 86 patients (mean age 76.26 years) over one year.
• Gait disorders were the most frequent symptom (94.2%).
• 92% of operated patients reported gait improvement at 6 weeks; older patients (>80) showed more improvement.

Conclusions:

• The Lausanne protocol offers a feasible, structured, and efficient diagnostic pathway for iNPH.
• The protocol particularly benefits older iNPH patients.
• This structured approach simplifies iNPH diagnosis and management.