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Updated: Jul 8, 2026

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

Sentinel Lymph Node Biopsy for Gynecologic Cancers.

Romelyn Imperio-Onglao1, Joseph Ng2

  • 1Clinical Associate Professor, College of Medicine, University of the Philippines; Consultant, Division of Gynecologic Oncology, Manila, Philippines.

Obstetrical & Gynecological Survey
|July 6, 2026
PubMed
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Sentinel lymph node biopsy (SLNBx) is effective for staging endometrial, vulvar, and cervical cancers, reducing surgical morbidity. Further research is needed to establish SLNBx for ovarian cancer treatment.

Area of Science:

  • Gynecologic Oncology
  • Surgical Pathology
  • Cancer Staging

Background:

  • Accurate lymph node metastasis assessment is vital for gynecologic cancer prognosis and treatment.
  • Sentinel lymph node biopsy (SLNBx) offers a less invasive alternative to traditional lymphadenectomy, improving patient quality of life.

Purpose of the Study:

  • This review assesses the efficacy, safety, and clinical utility of SLNBx in gynecologic cancers.
  • The aim is to guide clinical practice and identify future research directions.

Main Methods:

  • A comprehensive literature search was conducted across PubMed, Scopus, and Web of Science.
  • Included studies focused on endometrial, vulvar, cervical, and ovarian cancers, encompassing peer-reviewed articles, reviews, guidelines, and consensus statements.

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Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Published on: October 20, 2010

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Last Updated: Jul 8, 2026

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology
06:37

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Published on: October 20, 2010

Main Results:

  • SLNBx is validated for staging vulvar and endometrial cancers.
  • For cervical cancer, studies show high detection rates and comparable survival with reduced comorbidities.
  • Ovarian cancer SLNBx shows variable detection rates, necessitating further investigation.

Conclusions:

  • SLNBx is clinically supported for staging endometrial, vulvar, and cervical cancers.
  • Standardized protocols and continued research are required to integrate SLNBx into ovarian cancer management.