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Related Concept Videos

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Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
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Related Experiment Video

Updated: Jul 8, 2026

Measuring Delay Discounting in Humans Using an Adjusting Amount Task
07:47

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Published on: January 9, 2016

Polysubstance use: delay discounting in relationship to remission.

Fatima Quddos1, Devin C Tomlinson2, Rafaela M Fontes1

  • 1Fralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, VA, 24016, USA.

Scientific Reports
|July 6, 2026
PubMed
Summary

Delay discounting (DD) and recovery duration are linked to remission rates in polysubstance use disorder (polySUD). Modulating DD may improve recovery outcomes for individuals with polySUD history.

Keywords:
Delay discountingPolysubstance useProportion of remissionQuality of LifeRecovery

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Area of Science:

  • Addiction research
  • Clinical psychology
  • Behavioral neuroscience

Background:

  • Polysubstance use disorder (polySUD) is prevalent in contemporary addiction.
  • Assessing recovery progress in polySUD requires nuanced metrics beyond simple abstinence.
  • Proportion of remission (PrR) offers a continuous measure of recovery across multiple substances.

Purpose of the Study:

  • To investigate the association between delay discounting (DD) and proportion of remission (PrR) in individuals with polySUD.
  • To examine other recovery outcomes, such as maximum time in recovery and maximum quit time, in relation to PrR.
  • To explore potential mediating roles of DD and quit time in the relationship between recovery duration and PrR.

Main Methods:

  • Recruited 2,097 individuals with polySUD from the International Quit & Recovery Registry (IQRR).
  • Administered a $1000 adjusting amount delay discounting (DD) task.
  • Collected self-reported data on current/past substance use and recovery milestones.

Main Results:

  • Delay discounting (DD) was significantly associated with proportion of remission (PrR) in individuals with polySUD.
  • Maximum time in recovery and maximum quit time were also significantly associated with PrR.
  • The relationship between maximum time in recovery and PrR was serially mediated by DD and maximum quit time.

Conclusions:

  • Delay discounting (DD) and recovery duration are important factors in achieving proportion of remission (PrR) for individuals with polysubstance use disorder (polySUD).
  • Interventions targeting harm reduction and/or modulating DD may enhance clinical outcomes, including quit time and PrR, in polySUD populations.
  • The findings suggest that interventions aimed at improving decision-making processes related to delayed rewards could be beneficial for polysubstance users.