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Cosmetic Products Containing Rutin: A Systematic Review of Patents from 2014 to 2024
Maria Andréa da Silva1, Valéria Regina de Souza Moraes2, Raphael Amancio de Jesus1
1Department of Chemistry, Federal University of Sergipe, São Cristóvão, SE, Brazil.
Rutin, a natural flavonoid, is increasingly used in cosmetics for its antioxidant and anti-aging properties. Patent analysis reveals its potential in innovative formulations, often combined with other ingredients and advanced delivery systems.
Area of Science:
- Cosmetic Science and Technology
- Natural Product Chemistry
- Dermatology
Background:
- Rutin, a naturally occurring flavonoid, possesses scientifically validated benefits for cosmetic applications.
- Its antioxidant properties make it a valuable ingredient in cosmetic and dermocosmetic formulations.
Purpose of the Study:
- To analyze patents related to the cosmetic applications of rutin.
- To identify trends and innovations in rutin-based cosmetic formulations.
Main Methods:
- A comprehensive patent search was conducted across European, WIPO, and Brazilian intellectual property offices.
- The search strategy focused on 'rutin' in conjunction with cosmetic-related terms and classification codes (A61K8, C07H17).
Main Results:
- 38 patents were identified, with 27 focusing on anti-wrinkle, anti-aging, sunscreen, and antioxidant effects.
- 15 patents highlighted the botanical origin of rutin, indicating a trend towards plant-derived cosmetic ingredients.
- Formulations often combine rutin with synthetic actives for synergistic effects.
Conclusions:
- Structural modifications of rutin (e.g., polyglycosylated rutin, troxerutin) and advanced delivery systems (microencapsulation, nanoliposomes) enhance its efficacy.
- The patent landscape demonstrates significant innovation in optimizing rutin's physicochemical properties for cosmetic use.
- Local flora represents a promising source for novel cosmetic ingredient development.
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