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From HRO to HRE: Human-Centered Resilience Engineering as an Evolving Framework for Patient Safety Management
Oren Guttman1,2,3, Leah M Konwinski4, James Moses5
1Enterprise Vice President for High Reliability and Patient Safety, Jefferson Health, Philadelphia, PA, USA.
NEJM Catalyst Innovations in Care Delivery
|July 7, 2026
Summary
Patient safety progress has stalled, necessitating a shift towards future-ready, human-centered resilience engineering approaches in healthcare. This transformation requires renewed curiosity and collaboration within the healthcare safety community.
Area of Science:
- Healthcare Management
- Patient Safety Research
- Systems Engineering
Background:
- Patient safety progress has stagnated, despite increased calls for innovative approaches.
- Current quality measures show limited improvement, highlighting a need for advanced strategies.
- Healthcare organizations are increasingly open to new safety paradigms.
Purpose of the Study:
- To discuss the complexity of healthcare and the need for a transformed approach to patient safety.
- To describe the implementation of a human-centered resilience engineering approach in two health systems.
- To advocate for a collaborative and courageous advancement of patient safety practices.
Main Methods:
- Literature review on patient safety and healthcare complexity.
- Case study analysis of two health systems implementing resilience engineering.
- Qualitative assessment of organizational approaches to safety.
Main Results:
- Healthcare complexity necessitates a move beyond traditional safety measures.
- A human-centered resilience engineering approach can drive performance in complex healthcare systems.
- Successful implementation requires organizational openness and adaptation.
Conclusions:
- A transformed, human-centered resilience engineering approach is crucial for advancing patient safety.
- Collaboration, curiosity, and courage are essential for the healthcare safety community.
- Sharing knowledge and experiences will accelerate progress toward improved patient safety.
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