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Updated: Jul 8, 2026

Examining the Characteristics of Episodic Memory using Event-related Potentials in Patients with Alzheimer's Disease
Published on: August 30, 2011
[Autobiographical Memory in Alzheimer's Disease: Understanding to Better Support Patients]
Oumashankar Nunkessore1, Florence Bonfils2, Hélène Guedin3
1Court séjour gériatrique, hôpital Alexandra-Lepève, Dunkerque, France.
Abstract:
Autobiographical memory is central to the construction and maintenance of identity and psychosocial functioning. In Alzheimer's disease (AD), autobiographical memory progressively deteriorates, disrupting personal narratives and self-perception. This article provides an integrative review of current knowledge on autobiographical memory and its impairment in AD. Neuroanatomical correlates are discussed, highlighting the key role of the hippocampus and its interactions with the frontal and parietal cortices and the amygdala. Preserved cognitive resources and current supportive strategies, including multisensory stimulation, narrative reconstruction, and immersive approaches, are also examined. The role of family caregivers is emphasized, as mediators of memories, supporters of identity continuity, and contributors to shared memory processes. Future perspectives include the development of digital tools and integrative methodologies aimed at bridging experimental rigor and the lived experience of patients. Such approaches are essential for advancing our understanding of autobiographical memory decline in AD and for developing tailored interventions that support identity, autonomy, and psychosocial well-being.
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