Adenocarcinoma of the endometrium in pregnancy

Adenocarcinoma of the endometrium with intrauterine pregnancy is extremely rare. This report presents the finding of an adenoacanthoma of the endometrium discovered during therapeutic abortion and compares it with 6 other cases previously published. Four of the 7 tumors were adenocanthomas, a neoplasm that accounts for 20-30% of endometrial adenocarcinoma in the general population. Follow-up on 4 of the 6 previously reported patients indicates that 3 are well more than 5 years after diagnosis. The 1 patient who died of disease had an adenoacanthoma and was the only patient with extensive myometrial invasion at hysterectomy. The patient described in the present report is well 2 1/2 years after hysterectomy.