Related Experiment Video
Updated: Jul 9, 2026

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
Published on: April 6, 2022
Microbiota and immunotherapy: The birth of a new paradigm?
Rachel C Newsome1, Christian Jobin1
1Department of Medicine, University of Florida, Gainesville, FL, USA.
Abstract:
Emerging data suggest fecal microbiota transplantation (FMT) may improve cancer patients' responses to immune checkpoint blockade not only by enriching beneficial bacteria but also by depleting harmful taxa. Here, we discuss the "supplementation" and new "depletion" FMT paradigms in cancer management and highlight key knowledge gaps to be addressed to move this field forward.
More Related Videos
11:003D Flipwell Engineering for Developing Asynchronous Systems for Toxicologic and Immunomodulatory Therapies in Bacterial, Gut, and Immune Cells
Published on: October 17, 2025
07:32A Double Humanized BLT-mice Model Featuring a Stable Human-Like Gut Microbiome and Human Immune System
Published on: August 30, 2019
Related Concept Videos
Introduction to the Human Microbiota
Microorganisms in Medicine and Therapeutics
Microbiota Modulation by Antibiotics
Tumor Immunotherapy
Development of Human Microbiota
Gut-Brain Axis