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Updated: Jul 9, 2026
Fabrication of Mechanically Tunable and Bioactive Metal Scaffolds for Biomedical Applications
Published on: December 8, 2015
Si-modified beta-Ti-25Mo biomaterials with reduced elastic modulus, enhanced corrosion resistance, and
Krishan Kumar1, Mohit Kamboj2, Bodhisatwa Das2
1Department of Metallurgical and Materials Engineering, Indian Institute of Technology Ropar, Rupnagar, Punjab 140001, India.
Abstract:
One of the key challenges forβ-Ti alloys in biomedical applications is achieving a balance among low elastic modulus, high corrosion resistance, and cytocompatibility. In this study, Ti25MoxSi alloys (x= 0-2 wt.%) were designed to ensure a metastableβ-phase. The alloys were fabricated using vacuum arc melting. Their microstructures and surfaces were evaluated by optical microscopy and XRD to assess the constituting phases. The elastic modulus and hardness of the alloys were evaluated using nanoindentation. The corrosion behavior in aerated Ringer's solution using Electrochemical analysis. SEM, MTT assay, and live/dead cell assay were used to examine thein vitrobiological responses of all alloys. Optical microscopy shows equiaxedβ-Ti grains in all alloys, with ultrafine silicide precipitates at grain boundaries in 1.5 and 2 wt.% Si content. XRD analysis reveals stableβ-phase for all alloys. The nanoindentation studies show a reduced elastic modulus of 80-85 GPa. A significant enhancement in hardness was observed with typical values around 4 GPa. Preliminary electrochemical studies show improved corrosion resistance, suggesting the formation of a passive film upon adding Silicon.In vitrostudies using MC3T3-E1 cells confirm cytocompatibility across all compositions. The study highlights the potential of Ti-Mo-Si alloys for load-bearing biomedical implants.
