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High-concentration biologic formulations: challenges, strategies, and emerging technologies for subcutaneous delivery

Juan Ma1

  • 1Nona Biosciences (Shanghai) Co., Ltd., Shanghai, China.

European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V
|July 7, 2026
PubMed
Abstract

Keywords:
High-concentration formulationHyaluronidaseLyophilizationMicroglassificationProtein aggregationProtein crystallizationProtein viscositySpray dryingSubcutaneous injection

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