Related Experiment Video
Updated: Jul 9, 2026

An Implantable System For Chronic In Vivo Electromyography
Published on: April 21, 2020
Bilateral vocal cord paralysis in multifocal motor neuropathy
Talia Bartley1, Charlotte James2, Keir Edward Lewis2
1Respiratory Medicine, Prince Philip Hospital, Llanelli, Wales, UK talia.bartley@wales.nhs.uk.
None:
We present a case of a male in his fifties who attended with wheezing, dysphonia and shortness of breath. He was under investigation for asymmetrical muscle weakness in the absence of a sensory deficit for the preceding 1 year. Spirometry (flow volume loop) suggested extra-thoracic restriction and bronchoscopy confirmed bilateral vocal cord palsy. Due to clinical presentation and a positive anti-GM1, a diagnosis of multifocal motor neuropathy (MMN) with bilateral vocal cord palsy was made. The patient was initiated on intravenous immunoglobulin therapy with good effect on his general muscle weakness and respiratory symptoms, lung function and vocal cord abductor function. MMN with conduction block is a rare autoimmune condition, and vocal cord paresis from bilateral Xth cranial nerve involvement (recurrent laryngeal) is a very rare presentation of an MMN. Early diagnosis led to good patient outcomes.
Related Concept Videos
Myasthenia Gravis ll: Pathophysiology
Poliomyelitis
Botulism
Secondary Spinal Cord Injury llI: Pathophysiology
Myasthenia Gravis: Overview and Treatment
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which leads...
Myasthenia Gravis: Diagnostic Tests
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
