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Updated: Jul 9, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
Surpass evolve flow diverter in intracranial aneurysms: results from a single-center cohort with extended follow-up
Tae Keun Jee1, Hye Won Choi1, Je Young Yeon1
1Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Background:
The Surpass Evolve (SE) is a second-generation flow diverter (FD) designed to improve procedural performance compared with earlier devices. This study aimed to evaluate the angiographic efficacy, safety, and clinical outcomes of SE in a single-center cohort with extended follow-up, comparing it to earlier-generation FDs.
Methods:
We conducted a single-center comparative cohort study including 120 patients with unruptured intracranial aneurysms treated between 2014 and 2023. The prospective SE cohort (n = 67) was compared to a retrospective control cohort (n = 53; Surpass Streamline [SS] and Pipeline Embolization Device [PED]). Primary outcomes were complete aneurysm occlusion, major stroke, in-stent thrombosis, aneurysm enlargement, and unfavorable functional outcome. Secondary analyses included a composite safety endpoint and procedural parameters. Propensity score matching (PSM) was additionally performed to adjust for baseline imbalances, while multivariate Cox regression was used in the entire cohort to maximize statistical power.
Results:
Complete occlusion was achieved in 79.1% of the SE cohort, with major stroke and in-stent thrombosis occurring in 1.5% each, and aneurysm enlargement in 3.0%. At last follow-up, 98.5% of SE patients had favorable functional outcomes (mRS 0-2). Compared with controls, the SE cohort had significantly fewer major strokes (1.5% vs. 13.2%, p = 0.029) and lower aneurysm enlargement (3.0% vs. 22.6%, p = 0.002). These findings remained consistent in the PSM-matched cohort, particularly regarding the prevention of aneurysm enlargement (p = 0.012). Procedural time was shorter (p = 0.001), and balloon angioplasty was less frequent (p = 0.023). SE use was independently associated with reduced aneurysm enlargement (adjusted OR, 0.14; p = 0.019). Cox analysis showed SS had lower occlusion probability (HR, 0.58; p = 0.047) than SE, while PED was similar.
Conclusions:
In this single-center comparative cohort, SE demonstrated a favorable safety and efficacy profile, with lower rates of major stroke and aneurysm enlargement and improved procedural efficiency compared with earlier-generation devices.
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