Related Experiment Videos
Predictors of Recurrence Following Bronchial Artery Embolisation (BAE) for Haemoptysis: A Systematic Review and
Diya Sethi1, Tejas Ramnath Iyer2, Sinan Abu-Al-Timen2
1University of Buckingham Medical School, Hunter Street, Buckingham, MK18 1EG, UK. diyasethi12@gmail.com.
Cardiovascular and Interventional Radiology
|July 7, 2026
Summary
Recurrent haemoptysis after bronchial artery embolisation (BAE) is linked to chronic lung damage and abnormal blood vessel connections. Identifying these factors is key to improving BAE treatment success for patients with bleeding lungs.
Area of Science:
- Interventional Radiology
- Pulmonary Medicine
- Vascular Medicine
Background:
- Recurrent haemoptysis poses a significant clinical challenge.
- Bronchial artery embolisation (BAE) is a primary treatment for severe haemoptysis.
- Predictors of long-term BAE success require further elucidation.
Purpose of the Study:
- To systematically identify independent predictors of recurrent haemoptysis after BAE.
- To differentiate between etiological, anatomical, and procedural factors influencing recurrence.
- To utilize a Synthesis Without Meta-analysis (SWiM) framework for data synthesis.
Main Methods:
- Systematic literature search of PubMed, Cochrane, and Scopus databases.
- Inclusion of cohort studies reporting post-BAE haemoptysis recurrence.
- Data synthesis using a SWiM approach, prioritizing multivariable evidence.
- Assessment of evidence certainty using the GRADE framework.
Main Results:
- Sixty-five studies with 12,143 patients were included.
- Independent predictors of recurrence include systemic-pulmonary shunts, non-bronchial systemic collaterals (NBSCs), bronchiectasis, and prior haemoptysis history.
- Active tuberculosis, pulmonary malignancy, and concurrent anticoagulant use were neutral predictors.
Conclusions:
- Chronic lung destruction and systemic-pulmonary shunts are primary drivers of long-term BAE failure.
- Angiographic detection of collateral vessels and management of underlying conditions are crucial for BAE efficacy.
- Presentation characteristics and embolic agents play a lesser role in long-term recurrence.
Related Concept Videos
01:29Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
01:27Pulmonary Embolism III: Nursing Management
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
01:19Pulmonary Embolism I: Introduction
A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
01:29Pulmonary Embolism I: Introduction
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...