Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...

Disorders of Hemostasis

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.

Venous Thrombosis IV: Nursing Management

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...

Venous Thrombosis III: Interprofessional Care

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...

Introduction to Hemostasis

Introduction to Hemostasis

Hemostasis is a complex physiological process that prevents excessive bleeding when a blood vessel is injured. It's crucial for maintaining the integrity of the circulatory system, as it ensures that our blood remains fluid while still within the vascular network and yet clots to prevent blood loss upon vessel injury.
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized, and...

Extrinsic and Intrinsic Pathways of Hemostasis

Extrinsic and Intrinsic Pathways of Hemostasis

Blood clotting or coagulation involves extrinsic and intrinsic pathways, which ultimately merge into the common pathway, forming a fibrin clot.
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which forms a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Advanced Molecular Analysis in Hemophilia A in a Single Step: Next Generation Sequencing (NGS) and Copy Number Variation (CNV) Analysis.

International journal of laboratory hematology·2026

Same author

Citrullinated Histone 3 as a Marker of NETosis at Opposite Ends of Hemostasis: Evidence From Thrombosis-Prone MPN and Bleeding-Prone Hemophilia.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·2026

Same author

The Dilemma of Providing Advanced Hemophilia Treatments in Developing Countries - For Whom, by Whom and Where?

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·2026

Same author

National Perspectives on Academic CAR-T Cell Therapy in Türkiye: A report from Turkish Society of Hematology, Scientific Subcommittee on Cell and Gene Therapies (TSH-CGT SSC).

Turkish journal of haematology : official journal of Turkish Society of Haematology·2026

Same author

The role of CD36 expression on survival and febrile neutropenia in patients with acute myeloid leukemia.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals·2026

Same author

Evaluation of DNA methylation-based age prediction accuracy in leukemia patients using a six-CpG model trained on healthy blood.

Forensic science, medicine, and pathology·2026

Search research articles

Related Experiment Video

Updated: Jul 9, 2026

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

Published on: September 30, 2021

Haemophilia Management in Natural Disasters-From Field to Consensus Report.

Ahmet Muzaffer Demir¹, Selin Aytaç², Serap Karaman³

¹Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Trakya University, Edirne, Turkey.

Haemophilia : the Official Journal of the World Federation of Hemophilia

|July 8, 2026

Summary

This summary is machine-generated.

The Türkiye earthquake disrupted care for haemophilia patients, highlighting the need for disaster preparedness. Patients require accessible treatments and factor storage solutions during emergencies.

Keywords:

chronic disease consensus report disaster management earthquake haemophilia

More Related Videos

Prehospital Thrombolysis: A Manual from Berlin

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

Related Experiment Videos

Last Updated: Jul 9, 2026

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

Published on: September 30, 2021

Prehospital Thrombolysis: A Manual from Berlin

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

Area of Science:

Medical Sciences
Public Health
Disaster Medicine

Background:

The 2023 Türkiye earthquake severely impacted healthcare services and haemophilia patients.
This event underscored the vulnerability of individuals with bleeding disorders during extraordinary circumstances.

Purpose of the Study:

To identify the specific needs of haemophilia patients and physicians post-earthquake.
To assess challenges faced in healthcare service delivery for bleeding disorder patients in disaster zones.

Main Methods:

A cross-sectional survey study was conducted.
Data were collected via questionnaires for 10 severe haemophilia A and B patients and a 15-question focus group with 8 paediatric haematologists.
Key areas assessed included physical problems, treatment access, and factor storage.

Main Results:

Patients experienced bleeding, treatment access issues, and displacement.
Factor storage was compromised due to infrastructure damage and power outages.
Physicians faced difficulties in patient follow-up and assessing treatment needs due to damaged facilities and patient relocation.

Conclusions:

Managing chronically ill patients, including those with haemophilia, requires specialized disaster planning.
Patients stressed the importance of understanding their health status during crises.
Findings can inform guidelines for bleeding disorder management in emergencies.