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Updated: Jul 9, 2026

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva
Published on: July 5, 2017
Pathophysiological and molecular insights into allergic conjunctivitis: an expanding analysis of immunological
Henry Velazquez-Soto1, Lorenzo Islas-Vazquez1, Marisa Cruz-Aguilar1
1Department of Immunology, Research Unit, Institute of Ophthalmology Conde de Valenciana Foundation, Mexico City, Mexico.
Abstract:
Allergic conjunctivitis (AC) is an ocular surface disease characterized by immune-mediated inflammation that can significantly impair quality of life. This review explores recent advances in understanding the immunological and molecular mechanisms underlying AC, highlighting local and systemic immune responses and their roles in disease pathogenesis and progression. Particular attention is given to the influence of genetic and epigenetic factors, which may contribute to individual susceptibility and variability in clinical presentation. Finally, this review discusses emerging evidence on clinical phenotypes and immunological endotypes in ocular allergy, emphasizing their relevance for the development of targeted, personalized, and precision therapies.
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