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Pericardial Diseases in Cardiovascular Medicine: Contemporary Diagnosis, Risk Stratification, Multimodality Imaging,
1Division of Cardiology, Department of Medicine, Konkuk University Medical Center, 05030 Seoul, Republic of Korea.
Reviews in Cardiovascular Medicine
|July 8, 2026
Summary
Pericardial diseases can lead to chronic issues, but new imaging and targeted therapies like IL-1 inhibitors offer better management. This review focuses on recurrent pericarditis and precision-based treatment strategies.
Area of Science:
- Cardiology
- Inflammation Biology
Background:
- Pericardial diseases range from acute to chronic, with a significant portion developing persistent symptoms.
- Suboptimal early management and diagnostic uncertainty can worsen outcomes in pericarditis.
- Advances in imaging and targeted therapies are transforming pericardial disease management.
Purpose of the Study:
- To review current diagnostic and therapeutic strategies for pericardial diseases.
- To emphasize recurrent pericarditis and imaging-guided management.
- To propose a precision-based approach for optimizing patient outcomes.
Main Methods:
- Review of contemporary diagnostic and therapeutic strategies.
- Emphasis on multimodality imaging (echocardiography, CT, CMR).
- Integration of clinical risk stratification and targeted anti-inflammatory therapy.
Main Results:
- Multimodality imaging is crucial for anatomical assessment and differentiating inflammation from fibrosis.
- Interleukin-1 (IL-1) inhibitors show efficacy and steroid-sparing effects in refractory recurrent pericarditis.
- A stepwise, precision-based approach can optimize outcomes.
Conclusions:
- Contemporary management of pericardial diseases benefits from advanced imaging and targeted therapies.
- IL-1 inhibitors represent a significant advancement for refractory recurrent pericarditis.
- A precision-based strategy integrating imaging and targeted therapy is key for improved patient outcomes.
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