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Updated: Jul 9, 2026

Microwave-assisted Functionalization of Poly(ethylene glycol) and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
Published on: October 29, 2013
(Bis)methacrylamide zwitterionic dipeptide cross-linker synthesis and evaluation in polyampholyte hydrogels
Skyler O Oneida1, Adrienne Shea2, Matthew T Bernards2
1Department of Chemistry, University of Idaho Moscow ID 83844 USA kwaynant@uidaho.edu.
Abstract:
Polyampholyte hydrogels incorporating a novel dipeptide-based bis(methacrylamide) zwitterionic cross-linker (N-DAP-DAP-C) were synthesized and evaluated. N-DAP-DAP-C cross-linked hydrogels exhibited physical characteristics that were comparable to polyampholyte hydrogels formed with established zwitterionic cross-linkers. Further, N-DAP-DAP-C hydrogels demonstrated excellent resistance to Ralstonia pickettii adhesion during a 31-day evaluation.

