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Related Concept Videos

Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...

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Updated: Jul 10, 2026

Chronic Salmonella Infection Induced Intestinal Fibrosis
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Inflammatory bowel disease in the aging population.

Adam S Faye1, Bharati Kochar2,3,4, David Choi5

  • 1Inflammatory Bowel Disease Center, Division of Gastroenterology, Department of Medicine, NYU Langone Health, New York, NY 10016, United States.

Inflammatory Bowel Diseases
|July 8, 2026
PubMed
Summary

This review offers strategies for managing inflammatory bowel disease (IBD) in older adults by optimizing care for those over 60 and promoting healthy aging in those 40-60. It emphasizes medication management, screening, and vaccinations to improve quality of life.

Keywords:
elderlyfrailtygeriatricsinflammagingsarcopenia

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Area of Science:

  • Gastroenterology and Geriatrics
  • Inflammatory Bowel Disease Management

Background:

  • Rising inflammatory bowel disease (IBD) prevalence in older adults presents management challenges.
  • Age-related comorbidities, polypharmacy, and frailty complicate IBD care.

Purpose of the Study:

  • To propose a dual management approach for IBD patients aged >60 and 40-60.
  • To optimize care and promote healthy aging in IBD patients.

Main Methods:

  • Narrative review of current IBD management strategies for aging populations.
  • Emphasis on corticosteroid-sparing medications, medication reconciliation, and functional assessments.
  • Recommendations for screening, nutritional counseling, and vaccination schedules.

Main Results:

  • Optimized care for older IBD patients involves effective anti-inflammatory medications, dose adjustments, and medication review.
  • Promoting healthy aging in younger IBD patients includes early screening and nutritional support.
  • Vaccination adherence is crucial for immunosuppressed IBD patients.

Conclusions:

  • A proactive, personalized approach to IBD management is essential for older adults.
  • Strategies include tailored medication use, early interventions, and preventive care.
  • This approach can significantly enhance the quality of life for aging IBD patients.