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Related Experiment Video

Updated: Jul 10, 2026

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
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Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

Published on: August 12, 2018

Transforming static interfaces into tactile channels with steerable transdermal foci.

Qiutong Liu1,2, Yi Tang1, Jingyue Luo1

  • 1CTSIRI-PolyU Joint Lab, Department of Mechanical Engineering, The Hong Kong Polytechnic University, Hong Kong SAR, China.

Science Advances
|July 8, 2026
PubMed
Summary

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Transdermal Drug Delivery Systems01:18

Transdermal Drug Delivery Systems

Transdermal drug delivery systems (TDDS) enable the controlled release of drugs across the skin into systemic circulation. They are particularly advantageous for drugs with short half-lives or narrow therapeutic indices, as they maintain consistent plasma concentrations and reduce the risk of subtherapeutic or toxic levels.TDDS are categorized into monolithic, reservoir, and mixed systems. Monolithic systems embed the drug in a polymer matrix, where diffusion governs release. Reservoir systems...

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This study introduces transdermal all-directional targeting (TADT), a novel tactile display that transforms grip surfaces into active information channels. TADT enables efficient, high-resolution tactile communication for enhanced human-machine interaction.

Area of Science:

  • Human-Computer Interaction
  • Haptics
  • Biomedical Engineering

Background:

  • Tactile sensitivity of the hand is underutilized in human-machine interaction.
  • Existing interfaces often fail to leverage passive grip surfaces for information transfer.

Purpose of the Study:

  • To introduce transdermal all-directional targeting (TADT), a static-contact interface strategy.
  • To convert passive grip surfaces into active tactile displays for information transfer during grasping.

Main Methods:

  • TADT integrates a microtextured skin-coupling interface with phase-controlled vibrotactile actuation.
  • This design enhances energy delivery and generates steerable 3D tactile foci beneath the skin.
  • The system achieves high-frequency vibration (>200 Hz) and sub-actuator-pitch spatial super-resolution.

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Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
14:14

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

Published on: August 12, 2018

Main Results:

  • TADT lowers tactile detection thresholds by 30% and reduces power consumption by 80%.
  • Users reliably identified six directional cues using static grip alone.
  • Successful completion of nonvisual indoor navigation and virtual reality tasks was demonstrated.

Conclusions:

  • TADT offers a compact and energy-efficient modality for expressive tactile communication.
  • This technology enhances human-machine interaction by utilizing hand contact surfaces for information transfer.
  • TADT enables stable grasping while delivering evolving spatial and temporal tactile information.