Related Experiment Video
Updated: Jul 10, 2026

Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum
Published on: December 4, 2015
Molecular mechanisms underlying resistance to antimalarial compounds
1Division of Biological Chemistry and Drug Discovery, Faculty of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.
Abstract:
Drug resistance poses a major challenge to malaria control. Multiple strategies enable Plasmodium, the causative agent of malaria, to develop resistance against a broad range of antimalarial drugs. Comprehensive understanding of these mechanisms is crucial, not only for anticipating future threats but also for identifying molecular markers that can be used to monitor the emergence of drug resistance in field populations. This review summarizes the diverse pathways by which the parasite develops resistance, with a particular focus on recent mechanisms and next-generation antimalarial drugs under development.
More Related Videos
Related Concept Videos
Malaria
Antiprotozoal Agents
Anthelminthic Agents
Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu
Mechanism of Antibiotic Resistance in MRSA
Treatment Resistant Cancers

