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Updated: Jul 10, 2026

Ecosystem Fabrication (EcoFAB) Protocols for The Construction of Laboratory Ecosystems Designed to Study Plant-microbe Interactions
Published on: April 10, 2018
Engineering plant-associated microbiome for agriculture
Jingying Zhang1, Qianhang Zhai1, Yang Bai1
1State Key Laboratory for Gene Function and Modulation Research, Peking-Tsinghua Center for Life Sciences, Peking-Tsinghua-NIBS Graduate Program, New Cornerstone Science Laboratory, School of Life Sciences, Peking University, Beijing 100871, China.
Abstract:
Engineered plant-associated microbiomes provide a transformative approach for sustainable agriculture. In this Forum, we explore five strategies encompassing synthetic community design, native bacterial strain engineering, host-microbe co-adaptation, AI-driven design, and microbe-derived compounds. We assess the causes of repeated laboratory-to-field translation failures and argue for ecology-centric design principles.
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