Related Experiment Video
Updated: Jul 10, 2026

11:22
Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
Published on: October 15, 2019
Following Ariadne's thread through microbiome-based biomarker discovery in CRC
Jason Xing Kang1, Sunny Hei Wong2
1Centre for Microbiome Medicine, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore.
Cell Host & Microbe
|July 8, 2026
Abstract:
Colorectal cancer (CRC) carries a microbial fingerprint, but how does it generalize across age, geography, and sequencing platforms? In this issue of Cell Host & Microbe, Pekel and colleagues stitch together large-scale stool and tumor data to reveal a universal signal while exposing where stool-based biomarkers fall short.
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