Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

Source And Potency Of Stem Cells

Source And Potency Of Stem Cells

Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...

Adult Stem Cells

Adult Stem Cells

Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously renew...

Multipotency and Niche of Bulge Stem Cell

Multipotency and Niche of Bulge Stem Cell

A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...

Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Reference Genome Assembly of a Tetraploid Accession of the Tuber Crop Tropaeolum tuberosum.

Genome biology and evolution·2026

Same author

The role of DOF transcription factors for generating specificity in plant development.

Journal of experimental botany·2026

Same author

The Hidden Architects: Nitric Oxide and Redox Dynamics in Plant Stem Cell Homeostasis.

BioEssays : news and reviews in molecular, cellular and developmental biology·2025

Same author

A single-cell multi-omics atlas of rice.

Nature·2025

Same author

Strigolactones optimise plant water usage by modulating vessel formation.

Nature communications·2025

Same author

Mechanical forces instruct division plane orientation of cambium stem cells during radial growth in Arabidopsis thaliana.

Current biology : CB·2024

Search research articles

Related Experiment Video

Updated: Jul 10, 2026

Scalable 96-well Plate Based iPSC Culture and Production Using a Robotic Liquid Handling System

Scalable 96-well Plate Based iPSC Culture and Production Using a Robotic Liquid Handling System

Published on: May 14, 2015

Plant stem cell systems: Robust by design.

Thomas Greb¹, Jan U Lohmann¹

¹Centre for Organismal Studies, Heidelberg University, 69120 Heidelberg, Germany; Cluster of Excellence GreenRobust, Heidelberg University, 69120 Heidelberg, Germany.

Developmental Cell

|July 8, 2026

Summary

This summary is machine-generated.

Plant stem cells possess robust resilience not from genetic backup, but from distributed regulatory systems. These buffering mechanisms ensure continuous growth despite environmental changes.

Keywords:

Arabidopsis chromatin hormones mechanics organizer plant stem cells robustness single cell

More Related Videos

An Automated Culture System for Maintaining and Differentiating Human-Induced Pluripotent Stem Cells

An Automated Culture System for Maintaining and Differentiating Human-Induced Pluripotent Stem Cells

Published on: January 26, 2024

Related Experiment Videos

Last Updated: Jul 10, 2026

Scalable 96-well Plate Based iPSC Culture and Production Using a Robotic Liquid Handling System

Scalable 96-well Plate Based iPSC Culture and Production Using a Robotic Liquid Handling System

Published on: May 14, 2015

An Automated Culture System for Maintaining and Differentiating Human-Induced Pluripotent Stem Cells

An Automated Culture System for Maintaining and Differentiating Human-Induced Pluripotent Stem Cells

Published on: January 26, 2024

Area of Science:

Plant Biology
Developmental Biology
Genetics

Background:

Plants possess active stem cell populations throughout their lives.
These stem cell systems exhibit remarkable resilience to various perturbations.
Understanding the mechanisms behind this robustness is crucial for plant science.

Purpose of the Study:

To investigate the robustness of plant stem cell systems.
To identify the underlying regulatory architectures and buffering mechanisms.
To explore the implications for indeterminate plant growth.

Main Methods:

Synthesized evidence from shoot apical meristem, root apical meristem, and vascular cambium of Arabidopsis thaliana.
Analyzed regulatory architectures, including feedback loops, mobile transcription factors, hormonal fields, mechanical constraints, and chromatin dynamics.
Examined cell identity determination (position vs. lineage) and temporal decoupling of responses.

Main Results:

Plant stem cell robustness emerges from distributed regulatory architectures, not primarily genetic redundancy.
Multiple buffering layers, including negative feedback, mobile factors, hormonal fields, and mechanical/chromatin controls, contribute to resilience.
Cell identity is position-dependent, and environmental responses are decoupled from slow patterning.

Conclusions:

The resilience of plant stem cell systems is an emergent property of complex, distributed regulation.
Recurring design principles form a conserved and evolvable toolkit for indeterminate growth.
This toolkit enables plants to adapt and grow throughout their life cycle.