Related Experiment Video
Updated: Jul 10, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
Right- versus left-sided transvenous lead extraction: Procedural complexity, complications, outcomes, and the role of
Andrzej Kutarski1, Wojciech Jacheć1, Łukasz Tułecki2
12nd Department of Cardiology Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland.
Insights
Transvenous lead extraction (TLE) on the right side is more complex due to lead burden and bilateral systems, but outcomes remain comparable to left-sided TLE. This finding is crucial for understanding complex lead extraction procedures.
Area of Science:
- Cardiology
- Medical Devices
- Interventional Procedures
Background:
- Right-sided transvenous lead extraction (TLE) is a less common but significant subset of procedures.
- Anatomical variations and increased lead burden on the right side can complicate extraction compared to the left side.
Purpose of the Study:
- To compare procedural complexity, complications, and outcomes of TLE for right-sided (RS) leads versus left-sided only (LS) leads.
- To evaluate the impact of bilateral lead involvement in RS TLE.
Main Methods:
- Analysis of 4,288 consecutive TLE patients, with 121 (2.8%) involving RS leads.
- Comparison of RS procedures (unilateral and bilateral) against an entire LS cohort, with 1:2 matching for lead type and age.
- Detailed assessment of procedural parameters, technical difficulties, and complication rates.
Main Results:
- RS procedures exhibited higher lead burden, more abandoned leads (52% vs. 12%), longer dwell times (147 vs. 102 months), and increased technical difficulties (57% vs. 25%).
- Bilateral RS procedures were the most complex subgroup, associated with lower success rates.
- Major complications were more frequent in unmatched analysis but similar after matching; clinical success and long-term survival were comparable.
Conclusions:
- Right-sided TLE complexity is primarily driven by bilateral systems and lead factors, not the side of implantation.
- Despite increased procedural challenges, right-sided TLE does not negatively impact clinical or long-term patient outcomes.
Background:
Right-sided (RS) implanted leads represent a small but clinically relevant subset of transvenous lead extraction (TLE). Anatomical differences and greater lead burden may increase procedural complexity during extraction.
Objective:
To compare procedural complexity, complications, and outcomes TLE for RS and bilateral-sided vs left-sided only (LS) implanted leads.
Methods:
We analyzed 4288 consecutive patients undergoing TLE, including 121 (2.8%) with extraction of at least 1 RS lead and 4167 with LS leads only. Within the RS cohort, 76 procedures were unilateral and 45 (37%) involved bilateral lead extraction. Patients were compared with the entire LS cohort and after 1:2 matching for lead type and age of the oldest extracted lead.
Results:
RS procedures were associated with greater lead burden, more abandoned leads (52% vs 12%), more prior device-related procedures, and longer lead dwell time (147 vs 102 months). Procedural complexity was higher, including longer single-lead dilatation time (18 vs 11 minutes), more frequent technical difficulties (57% vs 25%), greater use of advanced extraction tools and more frequent change of venous access (27% vs 4%). Bilateral procedures represented the most complex subgroup and were associated with lower procedural success. Major complications were more frequent in the unmatched analysis but not after matching. Clinical success and long-term survival were comparable between groups.
Conclusion:
RS TLE is associated with increased complexity driven primarily by bilateral systems and lead-related factors, factors rather than implantation side itself, without adversely affecting clinical or long-term outcomes.
Related Concept Videos
Cardiac Catheterization III: Left Heart Catheterization
Cardiac Catheterization II: Right Heart Catheterization
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Cardiac Catheterization I: Pre-Procedure Overview
