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Updated: Jul 10, 2026

In Silico Modeling Method for Computational Aquatic Toxicology of Endocrine Disruptors: A Software-Based Approach Using QSAR Toolbox
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Published on: August 28, 2019

Salicylate esters inhibit human and rat 11β-Hydroxysteroid dehydrogenase type 2: Mechanistic insights from enzyme

Yinwei Dai1, Zhuoqi Chen2, Xiya Ren2

  • 1Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China; Department of Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China; Key Laboratory of Pediatric Anesthesiology, Ministry of Education, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China; Key Laboratory of Precision Anesthesiology of Zhejiang Province, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.

Toxicology and Applied Pharmacology
|July 8, 2026
PubMed

Keywords:
11β-hydroxysteroid dehydrogenase 2Cortisol metabolismHydrophobicitySPRSalicylateStructure-activity relationship

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