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Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds
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Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds

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Hit-To-Lead Optimization of a Pyridylpiperazine Class Against Malaria: Pharmacokinetic Profile and In Vivo Efficacy

Douglas Davison da Silva Oliveira1, Duarte Eduardo Pereira2, Rafael Consolin Chelucci3

  • 1Laboratório de Síntese de Candidatos a Fármacos (LaSFar), Institute of Chemistry, Federal University of Uberlândia (UFU), Uberlândia, MG, Brazil.

Chemmedchem
|July 8, 2026
PubMed

Keywords:
ADMEantimalarial activitydrug discoveryparasitic diseaseproof of concept

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