Two-Year Changes in Astigmatism in Myopic Children Wearing Lenslet-ARray-Integrated Spectacle Lenses

To investigate the effects of Lenslet-ARray-Integrated (LARI) spectacle lenses on refractive and corneal astigmatism in myopic children.

A secondary analysis of data from a randomized, double-masked trial.

Pertinent data were retrieved from the files of 209 participants from the previous 2-phase LARI study, which reported the efficacy of LARI lenses on myopia control in children aged 6 to 12 years.

Data from participants of the LARI study (phase I: wearing LARI lenses or single-vision (SV) lenses for 12 months; phase II: all wore LARI lenses for another 12 months) were retrieved and analyzed. Participants who wore LARI lenses for 2 years were categorized as the LARI group, whereas those who switched from SV to LARI lenses were categorized as the SV lens switched over to LARI lens in the second year (SV-LARI) group. Data retrieved included cycloplegic spherical equivalent refraction and refractive astigmatism, axial length, and corneal astigmatism at 6-month intervals, and the vector components (J0 and J45) of refractive and corneal astigmatism were calculated for analysis.

Changes in refractive and corneal astigmatism, J0, and J45.

No significant differences were found in increased refractive astigmatism, refractive J0 and J45, corneal astigmatism, and corneal J0 and J45 (all P > 0.05) between the LARI and SV groups in phase I. For participants who wore LARI lenses for 2 consecutive years, there were no significant differences in changes in refractive astigmatism and refractive J0 between phases I and II (P = 0.23 and P = 0.41), but change in J45 in phase II increased by -0.03 D (P = 0.003), and a smaller increase in corneal astigmatism was observed in the second year (0.07 ± 0.36 D vs. 0.20 ± 0.34 D, P = 0.02). In the SV-LARI group, a higher change in refractive astigmatism was observed in phase II (-0.12 ± 0.45 D, P = 0.03), but there were no significant differences in changes in refractive J0 and J45, corneal astigmatism, and corneal J0 and J45 between phases I and II (all P > 0.05).

Wearing LARI lenses for 2 years did not seem to lead to any clinically significant additional progression in refractive and corneal astigmatism.

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