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Related Experiment Video

Updated: Jul 10, 2026

Novel Surgical Rodent Model for Studying Neuroma Pain Treatment Options using Targeted Muscle Reinnervation Through the Saphenous Nerve
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Novel Surgical Rodent Model for Studying Neuroma Pain Treatment Options using Targeted Muscle Reinnervation Through the Saphenous Nerve

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Technical Considerations for Peripheral Nerve Sheath Tumor Excision With Intraoperative Neuromonitoring and

Carter J Boyd1, John N Muller1, Hailey P Wyatt1

  • 1From the Hansjörg Wyss Department of Plastic Surgery, NYU Langone Health, New York, NY.

Plastic and Reconstructive Surgery. Global Open
|July 9, 2026
PubMed
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This study details a surgical technique for peripheral nerve sheath tumor (PNST) excision, achieving low complication rates. The method involves nerve monitoring and microsurgical repair for effective PNST treatment.

Area of Science:

  • Neurosurgery
  • Oncology
  • Peripheral Nerve Surgery

Background:

  • Peripheral nerve sheath tumors (PNSTs) originate from Schwann cells and can cause pain and neurological deficits.
  • Limited literature exists on effective PNST excision techniques.
  • This study introduces a specific institutional surgical approach for PNST removal.

Purpose of the Study:

  • To describe and evaluate a surgical technique for the excision of peripheral nerve sheath tumors (PNSTs).
  • To present the outcomes and complication rates associated with this specific PNST excision method.

Main Methods:

  • Retrospective review of 69 patients undergoing 78 surgeries for PNSTs between 2009 and 2020.
  • Analysis of patient demographics, clinical presentation, surgical details, pathology, and postoperative outcomes.

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  • Inclusion of data on tumor characteristics, location, and surgical techniques employed, including nerve monitoring and repair.
  • Main Results:

    • 157 peripheral nerve tumors were excised, with neurofibromatosis type 1 being the most common diagnosis (41.0%).
    • Pain was the primary symptom (82.1%), and the upper extremity was the most frequent tumor location (48.7%).
    • The overall surgical complication rate was 2.7%, with neurological complications at 16.7%.

    Conclusions:

    • PNST excision presents reconstructive challenges.
    • Effective results with low complication rates can be achieved using intraoperative nerve monitoring, microsurgical instruments, and appropriate nerve repair techniques.
    • The described technique, including enucleation and nerve repair, offers a viable approach for PNST management.