Related Experiment Video
Updated: Jul 10, 2026

Doppler Ultrasound-Based Leg Blood Flow Assessment During Single-Leg Knee-Extensor Exercise in an Uncontrolled Setting
Published on: December 15, 2023
Effects of movement velocity in squat training with and without blood flow restriction
Pedro Jesús Cornejo-Daza1,2,3, Juan Sánchez-Valdepeñas1,4, Luis Rodiles-Guerrero1,5
1Science-Based Training Research Group, Physical Performance and Sports Research Center (CIRFD), Universidad Pablo de Olavide, Seville, Spain.
Abstract:
This study compared the effects of four different resistance training (RT) programs that differed in the movement velocity [maximum (MaxV) vs. 50% of maximum voluntary velocity (HalfV)] and the blood flow condition [free (FF) vs. restricted (BFR)] on strength, neuromuscular, and hypertrophy adaptations. Fortysix resistance-trained males were randomly assigned to one of the four abovementioned protocols. Subjects followed an 8-week RT program, twice per week, with similar intensity (55%-65% 1RM), sets (3), and repetitions per set (10-6) in the full-squat (SQ) exercise. Before and after the RT program, they were evaluated for: 1) muscle size of the vastus lateralis; 2) vertical jump; 3) maximal isometric contraction; 4) progressive loading test; and 5) fatigue test, in SQ. Electromyographic (EMG) activity was assessed during all SQ tests. All protocols exhibited significant gains in strength-derived parameters without significant differences between groups. A BFR × VEL × time interaction (p = 0.05) was observed for countermovement jump, with improvements in the HalfV-BFR and MaxV-FF protocols. A VEL × time interaction (p = 0.03) was found for the EMG amplitude under light loads, since HalfV-BFR increased its values. MaxV-BFR and HalfV-FF induced greater hypertrophy in the distal region of the vastus lateralis (BFR × VEL × time interaction, p = 0.04), with MaxV-BFR producing the greatest gains in all sections. Both MaxV-FF and HalfV-BFR increased CMJ height. HalfV-BFR also increased neuromuscular activity against light loads. MaxV-BFR and HalfV-FF evoked higher hypertrophy in muscle size, with the greatest gains in muscle size with MaxV-BFR.
Related Concept Videos
Blood Flow
Autoregulation of Blood Flow
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
Vascular Resistance
The primary determinants of vascular resistance are vessel diameter, blood viscosity, and vessel length. Among these, vessel diameter plays the most significant role due to the fourth power relationship described by...
