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Prescription Patterns in Rheumatoid Arthritis Patients at a Tertiary Care Hospital: A Prospective Cross-Sectional
Kaushalendra Mani1, Sujata Jadhav1, Vandana Thorat1
1Department of Pharmacology, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND.
Rheumatoid arthritis treatment in tertiary care centers relies heavily on conventional disease-modifying anti-rheumatic drugs (DMARDs), especially methotrexate. Biologics remain underutilized despite the condition
Area of Science:
- Rheumatology
- Pharmacology
- Epidemiology
Background:
- Rheumatoid arthritis (RA) is a global, chronic, systemic inflammatory disease.
- Medication prescription is a cornerstone of RA management.
- Understanding prescription patterns is crucial for optimizing patient care.
Purpose of the Study:
- To investigate the drug prescription patterns for rheumatoid arthritis patients.
- To analyze demographic and comorbidity profiles influencing treatment decisions.
- To assess the utilization of different drug classes in RA management.
Main Methods:
- Prospective, cross-sectional, descriptive study design.
- Inclusion of 95 rheumatoid arthritis patients.
- Data collection on demographics, comorbidities, and prescriptions, followed by analysis.
Main Results:
- RA predominantly affects middle-aged females (41-60 years; 66.3%) with moderate disease duration (3-5 years; 55.8%).
- Common comorbidities include hypertension (21.1%) and diabetes (16.8%).
- Disease-modifying anti-rheumatic drugs (DMARDs) were most prescribed (90.5%), particularly methotrexate (75.8%), followed by NSAIDs (64.2%) and corticosteroids (51.6%); biologics were limited (8.4%).
Conclusions:
- Rheumatoid arthritis impacts middle-aged females, often with comorbidities.
- Current treatment strategies show a strong preference for conventional DMARDs like methotrexate.
- Underutilization of biologics suggests potential areas for therapeutic advancement in RA management.
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