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Updated: Jul 10, 2026

Design, Surface Treatment, Cellular Plating, and Culturing of Modular Neuronal Networks Composed of Functionally Inter-connected Circuits

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A Multi-Stimuli Transformational Network of Benzil-Based Pd(II) Assemblies.

Zhiwei Zeng^1,2, A Priscila Gia^1,3, Alexander S Mikherdov¹

¹Department of Chemistry and Chemical Biology, TU Dortmund University, Dortmund, Germany.

Angewandte Chemie (International Ed. in English)

|July 9, 2026

Summary

Researchers developed a new ligand (L^A) for palladium(II) coordination assemblies, enabling control over structure and transformations. This ligand

Keywords:

chemical networks coordination cages post‐assembly modification self‐assembly supramolecular chemistry

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Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

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Published on: February 7, 2017

Area of Science:

Coordination chemistry
Supramolecular chemistry
Materials science

Background:

Precise control over supramolecular topology and nuclearity in coordination-driven self-assemblies is challenging.
Ligand design is crucial for directing self-assembly outcomes.

Purpose of the Study:

To introduce a flexible ligand (L^A) capable of adopting multiple conformations.
To explore the formation of diverse palladium(II) assemblies with varying topologies and nuclearities.
To investigate stimuli-responsive transformations of these assemblies.

Main Methods:

Synthesis of ligand L^A based on a benzil backbone.
Coordination of L^A with Pd(II) to form homoleptic and heteroleptic assemblies.
Characterization of resulting supramolecular structures.
Post-assembly modification via ligand condensation.

Main Results:

Formation of mononuclear (PdL^A₂) and cage (Pd₂L^A₄) homoleptic assemblies.
Synthesis of heteroleptic assemblies (cis-Pd₂L^A₂L^C₂, Pd₃L^A₂L^D₄) with secondary ligands.
Demonstration of interconversion and guest-induced transformations between architectures.
Post-assembly conversion to a rigid quinoxaline-based complex (PdL^B₂).

Conclusions:

Ligand conformation and assembly environment dictate structural outcomes and reactivity.
Demonstrated a stimuli-responsive system for dynamic control over supramolecular structures.
Highlighted the potential for mimicking natural systems' control over reactivity via confinement and allosteric effects.